The Lupus Support Network
P.O. Box 17841
Pensacola Fl  32522-7841
800.458.8211
850.478.8107
www.thelupussupportnetwork.org
questions@thelupussupportnetwork.org
What's In The
News?
Awareness
Month




June 27, 2014


Primary Endpoints Not Met in Phase II/III
Atacicept Trial


MedPage Today reports that atacicept did not meet primary endpoints in
the Phase II/III trial. Flare rates were not significantly less in the group of
patients treated at a lower 75 mg dose; while the rate was significantly
lower for patients receiving a higher 150 mg dose, two deaths due to
infections might have been associated with the drug.
The time to first flare (length of time person was in the study before
experiencing a flare) was significantly longer among those treated with
the 150 mg dose but not those who received the lower dose. Enrollment
in the 150 mg dose arm was terminated prematurely due to the two
deaths. Investigators feel the drug at the higher dose may still have
benefit but further study is needed to determine if there is a role for
atacicept in treating lupus.

Atacicept is a biologic agent that targets two B-cell factors being studied
in patients with moderate-to-severe lupus.  The study was reported on in
Annals of the Rheumatic Diseases.

- See more at:
Lupus Research Institute.






June 11, 2014


The LRI launches Industry Council to facilitate active collaboration among
companies, research leaders, and patient advocates to overcome
common obstacles in developing new treatments for #lupus.

Learn more about the collaboration here:
http://www.lupusresearchinstitute.org/lupus-news/2014/06/10/lupus-
research-institute-launches-industry-council-accelerate-new-treatments





December 17, 2012

Invion submitting Investigational Drug
Application Early 2013

The Australian company Invion met with the U.S. Food and Drug
Administration to discuss the roadmap for their drug INV103, and the FDA
agreed to its proposed indication of systemic lupus erythematosus. The
company will be submitting an Investigational New Drug Application early
in 2013.

INV103 is based on a naturally occurring protein, chaperonin10, which is
present in all cells. It is thought to function as a natural regulator of the  
immune system. Administering the protein can help regulate inflammation,
and can potentially be used to treat inflammatory diseases such as lupus.

- See more at:
Lupus Research Institute



L
upus Information in
Spanish:

Haga clic aquí para
obtener
información de
lupus en Español
Membership

It's important to everyone.
You don't have to have lupus to
be a member of
The Lupus Support Network.
Your membership supports our
programs in your community.
Membership Levels:

All memberships are good for a period of one year from your
anniversary month, the month when you originally joined. To
join, or renew your membership, please fill out the form below
a n d send t o :

Lupus Support Network, Inc.
P.O. Box 17841
Pensacola, Florida 32522-7841


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(Note: Complimentary memberships may be available to those
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Sharing and Caring, the bi-monthly newsletter will be sent to each
member whose dues are up to date. Other literature such as
edducational printed
materials distributed through support group meetings, by coming
into the office, or by calling and requesting information
to be sent to you.




(The Lupus Support Network , Inc. is a tax deductible, non-profit, charitable
organization)

Remember donations, not memberships, are tax deductible.

If you would like more information regarding
lupus or The Lupus Support Network contact
our office at
850.478.8107 or 800.458.8211
or via e-mail at
e-mail the Lupus Support Network

Could you have lupus?


Do you know the signs and symptoms
of lupus?

Do you know what questions to ask
your physician?

If you think you may have lupus, want to
know the signs and symptoms, or want to
know what to ask you physician visit:

Office of Women's Health Website for Lupus
Benlysta
The first drug approved by the FDA for the treatment of lupus in
over 50 years.

Since this announcement about the approval of Benlysta we have
been innundated with a lot of questions and concerns about the
drug.
To help everyone understand about the drug, to determine if they
are a candidate for this new drug, and answer general questions
we are posting the following information that came from the  
www.drugs.com website.

Benlysta is used for:

Treating certain patients with systemic lupus
erythematosus (SLE). It may also be used for
other conditions as determined by your doctor.

Benlysta is a B-lymphocyte stimulator
(BLyS)-specific inhibitor. Patients with lupus often
have high levels of a certain protein in their blood.
Benlysta works by limiting the activity of that
protein.
Do NOT use Benlysta if:

* you are allergic to any ingredient in Benlysta
* you have severe, active central nervous system
lupus
* you have certain severe kidney problems
associated with lupus (severe, active lupus
nephritis)
* you are using another biologic medicine (eg,
etanercept, infliximab, immune globulin)
* you are receiving cyclophosphamide as an
injection into your vein (intravenous [IV])

Contact your doctor or health care provider right
away if any of these apply to you.
Before using Benlysta:

Some medical conditions may interact with
Benlysta. Tell your doctor or pharmacist if you
have any medical conditions, especially if any of
the following apply to you:

* if you are pregnant, planning to become
pregnant, or are breast-feeding
* if you are taking any prescription or
nonprescription medicine, herbal preparation, or
dietary supplement
* if you have allergies to medicines, foods, or
other substances
* if you have a history of a long-term infection, an
infection that keeps coming back, tuberculosis
(TB) infection or a positive TB skin test, or
hepatitis B infection
* if you have an infection, open cuts or sores on
your body, flu-like symptoms or other signs of
infection (eg, fever; chills; cough; warm, red, or
painful skin), or are using medicine to treat an
infection
* if you have a history of cancer or heart problems
* if you have a history of mental or mood problems
(eg, depression), or suicidal thoughts or actions
* if you have recently received a vaccine or are
scheduled to receive a vaccine

Some MEDICINES MAY INTERACT with
Benlysta. Tell your health care provider if you are
taking any other medicines, especially any of the
following:

* Other biologic medicines (eg, etanercept,
infliximab, immune globulin), IV cyclophosphamide,
or monoclonal antibodies (eg, certolizumab,
denosumab) because the risk of their side effects
may be increased by Benlysta

This may not be a complete list of all interactions
that may occur. Ask your health care provider if
Benlysta may interact with other medicines that
you take. Check with your health care provider
before you start, stop, or change the dose of any
medicine.
Check out your local support group:

Brewton AL
2nd Wednesday of each month
D.W. McMillan Hospital
11:30 a.m.

Mobile Alabama
3rd Sunday of each month
3:00 p.m.
USA Children's & Women's Hospital - 3rd floor conference room

Pensacola
4th Saturday of each month
Lupus Office
Airport Blvd.
11:00 a.m.

Tallahassee
Second Saturday of the month
1:30 pm
B.L. Perry Library 2817 S. Adams St.

______________________________________

Support Groups Not Currently Meeting.
Contact us for more information.


Crestview

Ft. Walton Beach

Panama City